Where to start?
I. Think about the Functions of the musculoskeletal System
- Mineral homeostasis (Calcium, phosphorus)
- Housing for haematopoietic bone marrow elements
- Mechanical functions
- Protect viscera
- Movement and locomotion
- Body structure and size
II. Next, it may be helpful to begin by classifying the conditions into:
- BONE vs JOINT diseases
- FOUR major aetiologic categories: Inflamatory, Infectious, Metabolic and Neoplastic
- There are of course conditions that fall into other aetiologic categories (eg. traumatic, vascular, congenital, etc), however, we will focus on these four, in accordance with your lecture material.
Here’s a simple framework to start with:
- I. Bones
- Infectious diseases (osteomyelitis)
- Metabolic diseases (osteoporosis; osteomalacia/rickets; hyerparathyroidism; Paget’s disease)
- Neoplasms (Benign vs Malignant primary neoplasms; Metastatic malignancy)
- II. Joints
- Inflammatory diseases (eg. osteoarthritis – degenerative and inflammatory; rheumatoid arthritis; crystal arthropathies)
- Infectious diseases affect both bones (osteomyelitis) and joints (septic arthritis)
This mindmap explains a systematic Approach to Bone and Joint Diseases.