8 year old with acute lymphoblastic leukaemia with multi-organ involvement. He died of brain haemorrhage.
There is diffuse enlargement of the liver and spleen giving a pale homogenous cut appearance. The kidney is symmetrically enlarged with pale cortex and congested medulla. The brain shows intracerebral haemorrhage. The bowel wall shows patchy ulceration and haemorrhage. The vertebral column shows involvement of the vertebral bodies but no compression fracture.