8 year old boy with multi-organ involvement by acute lymphoblastic leukaemia. He died of brain haemorrhage with raised intracranial pressure.
The brain shows several foci of intracerebral haemorrhage.
There is diffuse enlargement of the liver, kidney and spleen giving a pale homogenous cut appearance. The kidney is symmetrically enlarged with pale cortex and medulla. No discrete nodular lesions are seen.
The vertebral column shows involvement of the vertebral bodies but no collapse or compression fracture.